NAD+ and NMN in Skincare: What the Longevity Trend Actually Means for Your Skin

The Skin Edit  ·  Ingredient Spotlight

NAD+ and NMN in Skincare: What the Longevity Trend Actually Means

By Lindsey Rapp, Licensed Esthetician & Registered Dietitian  ·  4 minute read

Hands holding a dropper bottle serum

NAD+ and NMN are two of the most talked about terms in longevity science right now, and that conversation has made its way into skincare. As a registered dietitian, I follow the longevity research closely, and here is how it actually translates to a topical product.

What Are NAD+ and NMN?

NAD+ is a coenzyme your cells rely on for basic energy production and repair processes, and levels naturally decline with age. NMN is a precursor your body can convert into NAD+. Most of the research on NAD+ and NMN comes from the longevity and cellular health space, and skincare formulations are a newer application of that research, applied topically rather than taken internally.

"I follow longevity science closely as part of my RD background, and it's what I use on my own skin."

Why This Interests Me as a Dietitian

Pfect-A NMN NAD+ Serum

Seeing longevity research applied to skincare is part of why I chose to bring the Pfect-A NMN and NAD+ Cellular Serum into the studio. It brings NAD+ focused formulation into a topical product, and it is what I use on my own skin.

Shop NMN and NAD+ Serum, $96 →

How It Fits Into a Routine

Use it as a treatment serum step, after cleansing and before moisturizer, alongside the rest of a consistent routine rather than as a stand alone solution. Like any active ingredient, results depend on consistency over time, not a single application.

Setting Realistic Expectations

Topical NAD+ and NMN skincare is a newer category, and most of the strongest research on these compounds comes from internal, cellular studies rather than topical application specifically. I recommend it as part of a well rounded routine, alongside fundamentals like hydration, barrier support, and daily SPF, not as a replacement for them.

Who This Is For

  • Anyone already following a consistent anti aging routine looking to add a newer, research adjacent ingredient
  • People interested in the longevity and cellular health space who want that philosophy reflected in their skincare
  • Skin that has already built a foundation of hydration and barrier support and is ready for an additional treatment step

Try It

Bring Longevity Science to Your Routine

Shop the NAD+ serum I use on my own skin.

Shop NMN and NAD+ Serum

FAQ

What does NAD+ do for skin?
NAD+ is a coenzyme involved in cellular energy production, and topical formulations are a newer application of the broader longevity research on this compound.

Is NMN skincare the same as NMN supplements?
No. Oral NMN supplements are a separate category from topical skincare, and this serum is formulated for external use as part of a skincare routine.

How does this fit with the rest of my routine?
Use it as a treatment serum step alongside your regular cleanser, moisturizer, and daily SPF rather than in place of them.

How long before I notice a difference?
As with most treatment serums, consistent use over several weeks is what allows an ingredient like this to do its work.

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